Worst SSRI's for weight gain
In response to the ongoing discussion about weight gain when taking Selective Serotonin Reuptake Inhibitors (SSRIs) I have added this post as I recently read some information that I found interesting.
Many people who take SSRI's for depression or anxiety suffer weight gain as a result. Indeed it is a common reason for people to prematurely break-off from otherwise beneficial treatment. But in truth, appearance is so key to modern life that it is no surprise that people who are already suffering from mood disorders don't want to get fat. This could lead to more depression!
It is important to point out that when taking SSRI's, weight gain can be mitigated against in more or less the same ways you would avoid gaining weight under normal circumstances. A good balanced diet with plenty of fresh fruit and vegetables and not too much saturated fat and sugars as found in junk food, and of course some exercise. You will also find that exercise helps with depression as this article shows. Seeings that you will have to talk to your doctor about the medication anyway, why not ask him or her to do a quick fitness assessment and check what level of exercise your body can take.
I was interested last week when I got an email from revolution health that linked to an article on their site about SSRI's that are known to cause weight gain. It is one of the most common questions I am asked so I am always on the look out for new material.
The table below shows what the article said, but I disagree with much of it. I personally have taken Celexa and found that it caused weight gain to the tune of 10KG! The table also shows escitalopram to be likely to cause weight gain. This is odd because citalopram (Celexa) and escitalopram (Lexapro) are almost identical. In the article and American academic stated that weight gain might be a sign that the drugs were having an effect. The professionals I have spoken to disagreed with this and thought that the point of view was outdated. I am not qualified to pass judgement on this. I would say though that the best indicator of efficacy when using SSRI anti-depressants is that the patients mood lifts!
These common drugs are likely to cause some weight gain - but that doesn't mean they definitely will!:
- Paxil (paroxetine)
- Marplan (isocarboxazid)
- Lexapro (escitalopram)
According to the article on Revolution Health these drugs generally don't cause weight gain (in my experience some definitely do!):
- Prozac (fluoxetine)
- Luvox (fluvoxamine)
- Zoloft (sertraline)
- Celexa (citalopram)
- Wellbutrin (buproprion)
I would be interested to here of other people's experiences with SSRI's and weight gain. You can email me info@anxiety2calm.com or leave a reply on this blog!
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8 Comments:
At 7:03 AM ,
Janna said...
I've heard of some people experiencing weight gain on Zoloft but I've never had a problem with it. Drugs affect people differently, that's for sure.
At 6:07 PM ,
Anonymous said...
I've been taking citalopram for a while & have gained a lot of weight.
At first I thought it was stopping smoking but that was over 4 years ago !!!
So having read all the list of possible side affects I can now identify with others too - nausea, insomnia, very dry mouth, etc....
So do I put up with this for the sake of a slight improvement in my mood or are there alternatives?
At 1:11 PM ,
Anonymous said...
Took citalopram for 4 months it worked fantastically for my so I gradually came off taking my last pill four weeks ago. I have gained weight but put that down to quitting smoking. I have in the last 2 weeks been feeling terrible, peaking today with a panic attack. Does anyone have any advice?!
At 2:12 PM ,
T P Chant said...
Hi anonymous! I have posted a response to your query here. Hope you are feeling better! Please post back if you have any more queries and me and anyone else will chip in with any more idea we have!
Hang in there!
At 1:00 AM ,
chaf kola said...
Hi All, I was put on luvox for anxiety and co morbid depression. A weight gain of nine kilos, in sixteen weeks and I said enough. It is possibly our condition causing the weight gain and not the drug. Bull bloody shit was my comment in thta my weight has been static almost all of my adult life (the only exception being when I got married) "well let us get you better and then worry about the weight". Again bull bloody shit. You are treating me for depression why should I be feeling depressed over weight gain that I don't have to have and then the penny started to drop about sexual dysfunction, lost libido, dry mouth, suicidal thoughts, increased urination, more frequent trips to the toilet, when getting there inability to pee, and the list just grew and grew. So it was relucantly agreed to take me off this drug. I have refused any further medications and belive I am a million times better than when on these mind altering drugs.
Chaf.
At 4:36 PM ,
Anonymous said...
I have being taking escitalopram on a high dose of 20mg for the last 1.5 years- it has been a fantastic drug for my generalised anxiety and ocd type symptoms, have tried a number before with little help. but this one really has calmed my mind and being a great help. however, the only bad symptoms i have experienced is i have gained about 7-8 lb which whatever i do i cannot seem to lose. have been excersising about 4-5 times a week, eating very healthy and it will not budge. however maybe this is a good thing as i don't want to be on it forever and this is now pushing me to discuss with my dr coming of it slowly. However i really would encourage people not to be scared by this, everyones metabolism is different and drugs will have different affects. if like me your life has been so filled with anxiety really putting on a little weight for a short time is not the end of the world. thanks,
At 1:45 AM ,
Anonymous said...
I have taken Prozac for a number of years with no noticable change in weight. Recently I was on Citalopram for 2 years again with no changes. I moved onto Escitalopram and within 9 months have put on 28 pounds.My diet/exersize has not changed in this time the ONLY difference was the Escitalopram. Just in the process of changing to Prozac again.
Apart fronm the weight gain, it was the best SSRI I have tried.
At 2:01 PM ,
Anonymous said...
I've tried numerous antidepressants for the past 10 yrs. I have always gained about 25 lbs. with each medication. I would then stop the medication and loose the weight; depression would return and I would try a different antidepressant. I have now been on Celexa for about two years and have been 25-30 lbs. over my normal weight. It is very depression but I have stayed on the medication because I am afraid of the depression returning; but am getting very depressed about the weight. The only medication that did not cause weight gain for me was Serzone, which I took for about 2 yrs. My doctor took me off because of the black box warning. I went through the worst withdrawal ever! I HATE depending on these horrible drugs!!!!
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